GSTP1 anticorps (AA 5-210)

N° du produit ABIN968135

Détail du produit anti-GSTP1 anticorps

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Épitope: AA 5-210

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GSTP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Réactivité croisée: Souris, Rat (Rattus), Chien

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human GST-pi aa. 5-210

Clone: 3-GST

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN967389, ABIN968535

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-GSTP1 (ABIN968135)

Ali-Osman, Akande, Antoun, Mao, Buolamwini: "Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins." dans: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10004-12, (1997) (PubMed).

Zhou, Evans, London, Xia, Zou, Shen, Clapper: "Glutathione S-transferase expression in hepatitis B virus-associated human hepatocellular carcinogenesis." dans: Cancer research, Vol. 57, Issue 13, pp. 2749-53, (1997) (PubMed).

Kano, Sakai, Muramatsu: "Structure and expression of a human class pi glutathione S-transferase messenger RNA." dans: Cancer research, Vol. 47, Issue 21, pp. 5626-30, (1987) (PubMed).

Détails sur GSTP1

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: GST-pi (GSTP1 Produits)

Synonymes: anticorps DFN7, anticorps FAEES3, anticorps GST3, anticorps GSTP, anticorps PI, anticorps GST-P, anticorps Gst3, anticorps Gstp, anticorps Gstp2, anticorps gst-Pi, anticorps GstpiB, anticorps glutathione S-transferase P-like, anticorps glutathione S-transferase pi 1, anticorps glutathione S-transferase pi 1 L homeolog, anticorps glutathione S-transferase, pi 1, anticorps LOC100739163, anticorps GSTP1, anticorps Gstp1, anticorps LOC100861197, anticorps gstp1.L

Sujet: Glutathione-S-Transferases (GSTs) are a family of dimeric proteins that catalyze the S-conjugation of glutathione with many compounds for detoxification. The GSTs are categorized into four classes based on their biochemical and structural properties: alpha, µ, pi, and theta. GST-pi is of particular interest because it is over-expressed in many tumors, but is either absent or expressed at low levels in the corresponding normal tissues. This high expression of GST-pi is associated with malignant transformation and correlates with a decrease in GST activity. Three different GST-pi proteins have been isolated and designated as hGSTP1A, hGSTP1B, and hGSTP1C. These isoforms are nearly identical, varying by only one to two amino acids. This antibody is routinely tested by western blot analysis.
Synonyms: Glutathione-S-Transferase-pi

Poids moléculaire: 23 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin