HAX1 anticorps (AA 10-148)

N° du produit ABIN968199

Cet anticorps anti-HAX1 est un anticorps Souris Monoclonal détectant HAX1 dans WB, IHC, IF et IP. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour HAX1 anticorps (AA 10-148) (ABIN968199)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 52-HAX

Détail du produit anti-HAX1 anticorps

Épitope: AA 10-148

Réactivité croisée: Rat (Rattus), Souris

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human HAX-1 aa. 10-148

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968537, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-HAX1 (ABIN968199)

Suzuki, Demoliere, Kitamura, Takeshita, Deuschle, Watanabe: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX-1

Sujet: Cell-cell interactions in the immune system, mediated by membrane-bound antigen receptors, trigger a cascade of signaling mechanisms collectively known as the T-cell response. Upon antigen binding, cellular tyrosine kinases are activated resulting in the phosphorylation of HS1 or Lck-binding protein 1 (LckBP1), which is involved in thymic negative selection. HS1 is one of the earliest intracellular proteins to be tyrosine phosphorylated in response to antigen-receptor cross-linking in T cells. HAX-1 (HS1-associated protein X-1) is a 35 kDa protein found associated with HS1 by co-immunoprecipitation assays and the two-hybrid system. HAX-1 is ubiquitously expressed and localized in the mitochondria, endoplasmic reticulum, and the nuclear envelope. The HS1-HAX-1 complex may be critical for signal transduction pathways initiated by antigen presentation to T cells.

Poids moléculaire: 35 kDa

Pathways: Regulation of Actin Filament Polymerization