Striatin anticorps (AA 450-600)

N° du produit ABIN968207

L’anticorps Souris Monoclonal anti-Striatin a été validé pour WB et IF. Il convient pour détecter Striatin dans des échantillons de Humain, Souris, Rat et Chien. Il y a 2+ publications disponibles.

Aperçu rapide pour Striatin anticorps (AA 450-600) (ABIN968207)

Antigène: Striatin (STRN)

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Striatin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 6-Striatin

Détail du produit anti-Striatin anticorps

Épitope: AA 450-600

Réactivité croisée: Souris, Humain, Chien

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Rat Striatin aa. 450-600

Isotype: IgG2b

Information d'application

Commentaires:

Related Products: ABIN968545, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-Striatin (ABIN968207)

Castets, Rakitina, Gaillard, Moqrich, Mattei, Monneron: "Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain." dans: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19970-7, (2000) (PubMed).

Castets, Bartoli, Barnier, Baillat, Salin, Moqrich, Bourgeois, Denizot, Rougon, Calothy, Monneron: "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons." dans: The Journal of cell biology, Vol. 134, Issue 4, pp. 1051-62, (1996) (PubMed).

Détails sur Striatin

Antigène: Striatin (STRN)

Autre désignation: Striatin

Sujet: Signal transmission between neurons is regulated by the Ca2+-dependent release of neurotransmitters at the synapse. Striatin is a protein identified in the synaptosomal fraction of rat brain. Reports of sequence homology searches have shown that striatin belongs to a family of proteins with the repeated WD motif (the beta-transducin repeat or the WD-40 repeat) found in regulatory proteins. Striatin also binds calmodulin in a Ca2+-dependent manner. Immunolocalization and mRNA expression found striatin in the central nervous system, particularly enriched in neurons of the striatum and motor neurons. Furthermore, subcellular localization studies indicated that Striatin is tightly associated with the plasma membrane. Thus, striatin may play an important role in the Ca2+-dependent events occurring at the synapse.

Poids moléculaire: 110 kDa

Pathways: Nuclear Hormone Receptor Binding, Cell-Cell Junction Organization