EZH2 anticorps (AA 156-256)

N° du produit ABIN968906

L’anticorps Souris Monoclonal anti-EZH2 a été validé pour WB et IF. Il convient pour détecter EZH2 dans des échantillons de Humain, Souris, Rat, Chien et Poulet. Il y a 2+ publications disponibles.

Aperçu rapide pour EZH2 anticorps (AA 156-256) (ABIN968906)

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivité: Humain, Souris, Rat, Chien, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EZH2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 11-EZH2

Détail du produit anti-EZH2 anticorps

Épitope: AA 156-256

Réactivité croisée: Chien, Rat (Rattus), Souris, Poulet

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human EZH2 recombinant protein aa. 156-256

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968537, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-EZH2 (ABIN968906)

Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: "Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 5925-34, (2001) (PubMed).

van Kemenade, Raaphorst, Blokzijl, Fieret, Hamer, Satijn, Otte, Meijer: "Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma." dans: Blood, Vol. 97, Issue 12, pp. 3896-901, (2001) (PubMed).

Détails sur EZH2

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: EZH2

Sujet: The Polycomb group (PcG) of gene products are essential for the maintenance, but not initiation, of the transcriptionally repressed state of development genes. Those genes encode a structurally diverse group of proteins with conserved functions from flies to human cells and from complexes as a result of mutual associations ultimately influencing gene expression. EZH2 is a human homologue of Drosophil's Enhancer of Zeste gene, an important regulator of homeobox gene expression. The expression of EZH2 was seen in follicular T cells and at different stages during T-cell differentiation. Additionally, in lymphocytes, EZH2 interacts with the signal transduction protein Vav and is highly expressed in a variety of tumors such as lymphoma and prostate. The predicted molecular weight for this protein is approximately 85 kDa (SwissProt:Q15910).

Poids moléculaire: 91 kDa

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation