CD90 anticorps (APC)

N° du produit ABIN968931

Détail du produit anti-CD90 anticorps (APC)

Antigène: CD90 (THY1)

Reactivité: Humain, Porc, Non-Human Primate, Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD90 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Specificité: The mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.

Aucune reactivité croisée: Chien

Réactivité croisée (Details): Human, Non-Human Primates, Porcine, Equine (Horse)

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: HEL erythroleukemia cells

Clone: 5E10

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CD90 (APC) (ABIN968931)

Hoppstädter, Diesel, Zarbock, Breinig, Monz, Koch, Meyerhans, Gortner, Lehr, Huwer, Kiemer: "Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages." dans: Respiratory research, Vol. 11, pp. 124, (2010) (PubMed).

Kroeze, Jurgens, Doulabi, van Milligen, Scheper, Gibbs: "Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES." dans: The Journal of investigative dermatology, Vol. 129, Issue 6, pp. 1569-81, (2009) (PubMed).

Carlsten, Björkström, Norell, Bryceson, van Hall, Baumann, Hanson, Schedvins, Kiessling, Ljunggren, Malmberg: "DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells." dans: Cancer research, Vol. 67, Issue 3, pp. 1317-25, (2007) (PubMed).

St Louis, Woodcock, Franzoso, Blair, Carlson, Murillo, Wells, Williams, Smoot, Kaushal, Grimes, Harlan, Chute, June, Siebenlist, Lee, Fransozo: "Evidence for distinct intracellular signaling pathways in CD34+ progenitor to dendritic cell differentiation from a human cell line model." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 6, pp. 3237-48, (1999) (PubMed).

Ito, Inaba, Inaba, Toki, Sogo, Iguchi, Adachi, Yamaguchi, Amakawa, Valladeau, Saeland, Fukuhara, Ikehara: "A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 3, pp. 1409-19, (1999) (PubMed).

Détails sur CD90

Antigène: CD90 (THY1)

Autre désignation: CD90 (THY1 Produits)

Synonymes: anticorps CD90, anticorps CD7, anticorps T25, anticorps Thy-1, anticorps Thy-1.2, anticorps Thy1.1, anticorps Thy1.2, anticorps Thy-1 cell surface antigen, anticorps thymus cell antigen 1, theta, anticorps THY1, anticorps Thy1

Sujet: Thy-1 cell surface antigen,CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.,Thy-1

ID gène: 7070

UniProt: P04216

Pathways: Cell-Cell Junction Organization