LIN28A anticorps (AA 93-209)

N° du produit ABIN968936

L’anticorps Souris Monoclonal anti-LIN28A a été validé pour ELISA et ICC. Il convient pour détecter LIN28A dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour LIN28A anticorps (AA 93-209) (ABIN968936)

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LIN28A est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Clone: 6D1F9

Détail du produit anti-LIN28A anticorps

Épitope: AA 93-209

Fonction: LIN28 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-LIN28A (ABIN968936)

Gerecht-Nir, Dazard, Golan-Mashiach, Osenberg, Botvinnik, Amariglio, Domany, Rechavi, Givol, Itskovitz-Eldor: "Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem cells." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 232, Issue 2, pp. 487-97, (2005) (PubMed).

Wu, Belasco: "Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells." dans: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9198-208, (2005) (PubMed).

Détails sur LIN28A

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Autre désignation: LIN28

Sujet: LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.

Poids moléculaire: 23 kDa

ID gène: 79727

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance