AAT anticorps

N° du produit ABIN968939

Il existe 2+ publications pour ce produit. L’anticorps anti-AAT Monoclonal Souris est utilisé pour la détection de AAT dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour AAT anticorps (ABIN968939)

Antigène: AAT

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Clone: 2B12

Détail du produit

Fonction: AAT Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human AAT expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Référence

El-Akawi, Al-Hindawi, Bashir: "Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients." dans: Neuro endocrinology letters, Vol. 29, Issue 4, pp. 482-4, (2008) (PubMed).

Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." dans: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, (2005) (PubMed).

Détail du antigène

Antigène: AAT

Sujet: AAT, also known as SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.

Poids moléculaire: 47 kDa

ID gène: 5265

UniProt: P01009