AAT anticorps

N° du produit ABIN968939

Détail du produit

Antigène: AAT

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human AAT expressed in E. coli.

Clone: 2B12

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Référence

El-Akawi, Al-Hindawi, Bashir: "Alpha-1 antitrypsin (alpha1-AT) plasma levels in lung, prostate and breast cancer patients." dans: Neuro endocrinology letters, Vol. 29, Issue 4, pp. 482-4, (2008) (PubMed).

Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." dans: Journal of proteome research, Vol. 4, Issue 6, pp. 2070-80, (2005) (PubMed).

Détail du antigène

Antigène: AAT

Synonymes: anticorps A1A, anticorps A1AT, anticorps AAT, anticorps PI, anticorps PI1, anticorps PRO2275, anticorps alpha1AT, anticorps serpin family A member 1, anticorps SERPINA1

Sujet:

Description: AAT, also known as SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.

Aliases: PI, A1A, AAT, PI1, A1AT, SERPINA1

Poids moléculaire: 47 kDa

ID gène: 5265

HGNC: 5265