ABL2 anticorps

N° du produit ABIN968943

Cet anticorps anti-ABL2 est un anticorps Souris Monoclonal détectant ABL2 dans ELISA et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour ABL2 anticorps (ABIN968943)

Antigène: ABL2

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ABL2 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Clone: 1H1B11

Détail du produit anti-ABL2 anticorps

Fonction: ABL2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of ABL2 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ABL2 (ABIN968943)

Scheijen, Griffin: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." dans: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).

Iijima, Ito, Oikawa, Eguchi, Eguchi-Ishimae, Kamada, Kishi, Asano, Sakaki, Sato: "A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation." dans: Blood, Vol. 95, Issue 6, pp. 2126-31, (2000) (PubMed).

Détails sur ABL2

Antigène: ABL2

Autre désignation: ABL2

Sujet: ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.

ID gène: 27

UniProt: P42684