c-Rel anticorps

N° du produit ABIN968997

Cet anticorps anti-c-Rel est un anticorps Souris Monoclonal détectant c-Rel dans WB, ELISA, IHC et ICC. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour c-Rel anticorps (ABIN968997)

Antigène: c-Rel (REL proto-oncogene (c-Rel))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-Rel est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 1E7

Détail du produit anti-c-Rel anticorps

Fonction: c-Rel Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human c-Rel expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-c-Rel (ABIN968997)

Trynka, Zhernakova, Romanos, Franke, Hunt, Turner, Bruinenberg, Heap, Platteel, Ryan, de Kovel, Holmes, Howdle, Walters, Sanders, Mulder, Mearin, Verbeek, Trimble, Stevens, Kelleher, Barisani et al.: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. ..." dans: Gut, Vol. 58, Issue 8, pp. 1078-83, (2009) (PubMed).

Garbati, Gilmore: "Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation." dans: Gene expression, Vol. 14, Issue 4, pp. 195-205, (2008) (PubMed).

Détails sur c-Rel

Antigène: c-Rel (REL proto-oncogene (c-Rel))

Autre désignation: c-Rel

Sujet: The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.

Poids moléculaire: 68.5 kDa

ID gène: 5966

UniProt: Q04864