CARM1 anticorps

N° du produit ABIN969002

2+ publications sont disponibles pour ce produit. L’anticorps anti-CARM1 Monoclonal produit chez le Souris a été validé pour WB, ELISA, IHC, FACS et ICC. Il convient pour la détection de CARM1 dans des échantillons provenant de Humain, Rat et Singe. }

Aperçu rapide pour CARM1 anticorps (ABIN969002)

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Reactivité: Humain, Rat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CARM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3H2

Détail du produit anti-CARM1 anticorps

Fonction: CARM1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CARM1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CARM1 (ABIN969002)

Fauquier, Duboé, Joré, Trouche, Vandel: "Dual role of the arginine methyltransferase CARM1 in the regulation of c-Fos target genes." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 9, pp. 3337-47, (2008) (PubMed).

Kleinschmidt, Streubel, Samans, Krause, Bauer: "The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation." dans: Nucleic acids research, Vol. 36, Issue 10, pp. 3202-13, (2008) (PubMed).

Détails sur CARM1

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Autre désignation: CARM1

Sujet: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Poids moléculaire: 65 kDa

UniProt: Q86X55

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation