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CCT2 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement CCT2 dans WB, ELISA, ICC et FACS. Il présente une réactivité envers Humain, Souris, Rat et Singe et a été mentionné dans 2+ publications.
N° du produit ABIN969010

Aperçu rapide pour CCT2 anticorps (ABIN969010)

Antigène

Voir toutes CCT2 Anticorps
CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Reactivité

  • 59
  • 42
  • 24
  • 8
  • 8
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Singe

Hôte

  • 51
  • 8
  • 1
Souris

Clonalité

  • 47
  • 13
Monoclonal

Conjugué

  • 33
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CCT2 est non-conjugé

Application

  • 46
  • 14
  • 13
  • 13
  • 12
  • 9
  • 9
  • 8
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

5B5C4
  • Fonction

    CCT2 Antibody

    Purification

    Ascitic fluid

    Immunogène

    Purified recombinant fragment of human CCT2 expressed in E. Coli.

    Isotype

    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Abe, Yoon, Kubota, Mendoza, Gygi, Blenis: "p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling." dans: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14939-48, (2009) (PubMed).

    Goudreault, DAmbrosio, Kean, Mullin, Larsen, Sanchez, Chaudhry, Chen, Sicheri, Nesvizhskii, Aebersold, Raught, Gingras: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." dans: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, (2009) (PubMed).

  • Antigène

    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

    Autre désignation

    CCT2

    Sujet

    The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.

    Poids moléculaire

    54 kDa

    UniProt

    P78371
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