Endoglin anticorps

N° du produit ABIN969012

Cet anticorps anti-Endoglin est un anticorps Souris Monoclonal détectant Endoglin dans FACS, IHC, ELISA et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Endoglin anticorps (ABIN969012)

Antigène: Endoglin (ENG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 3A9

Détail du produit anti-Endoglin anticorps

Fonction: CD105 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CD105 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Endoglin (ABIN969012)

Valeria, Maddalena, Enrica, Onofrio, Gaetano: "Endoglin (CD105) expression in the human heart throughout gestation: an immunohistochemical study." dans: Reproductive sciences (Thousand Oaks, Calif.), Vol. 15, Issue 10, pp. 1018-26, (2008) (PubMed).

Fujita, Ewing, Chan, Mangold, Partin, Isaacs, Pavlovich: "Endoglin (CD105) as a urinary and serum marker of prostate cancer." dans: International journal of cancer. Journal international du cancer, Vol. 124, Issue 3, pp. 664-9, (2008) (PubMed).

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105

Sujet: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.

Poids moléculaire: 71 kDa

UniProt: P17813