CHD3 anticorps

N° du produit ABIN969052

Cet anticorps Souris Monoclonal détecte spécifiquement CHD3 dans WB, IHC, ELISA, ICC et FACS. Il présente une réactivité envers Humain et Souris et a été mentionné dans 1 publication.

Aperçu rapide pour CHD3 anticorps (ABIN969052)

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CHD3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 2G4

Détail du produit anti-CHD3 anticorps

Fonction: CHD3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CHD3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CHD3 (ABIN969052)

Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." dans: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).

Détails sur CHD3

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Autre désignation: CHD3

Sujet: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Poids moléculaire: 226 kDa

UniProt: Q12873