CIB1 anticorps

N° du produit ABIN969057

Cet anticorps anti-CIB1 est un anticorps Souris Monoclonal détectant CIB1 dans WB, ELISA et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour CIB1 anticorps (ABIN969057)

Antigène: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CIB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 5A1F5E12

Détail du produit anti-CIB1 anticorps

Fonction: CIB1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of CIB1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CIB1 (ABIN969057)

White, Yang, Monteiro, Foskett: "CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel." dans: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20825-33, (2006) (PubMed).

Gentry, Singer, Betts, Yang, Ferrara, Sondek, Parise: "Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins." dans: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8407-15, (2005) (PubMed).

Détails sur CIB1

Antigène: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Autre désignation: CIB1

Sujet: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

UniProt: Q99828