CRTC2 anticorps

N° du produit ABIN969067

Cet anticorps Souris Monoclonal détecte spécifiquement CRTC2 dans WB, ELISA, IHC, FACS et ICC. Il présente une réactivité envers Humain et Singe et a été mentionné dans 3+ publications.

Aperçu rapide pour CRTC2 anticorps (ABIN969067)

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRTC2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 5B10

Détail du produit anti-CRTC2 anticorps

Fonction: CRTC2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CRTC2 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CRTC2 (ABIN969067)

Murata, Sato, Nakayama, Kudoh, Iwahori, Isomura, Tajima, Hishiki, Ohshima, Hijikata, Shimotohno, Tsurumi: "TORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 protein." dans: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 8033-41, (2009) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Dentin, Liu, Koo, Hedrick, Vargas, Heredia, Yates, Montminy: "Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2." dans: Nature, Vol. 449, Issue 7160, pp. 366-9, (2007) (PubMed).

Détails sur CRTC2

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Autre désignation: CRTC2

Sujet: Glucose homeostasis is regulated by hormones and cellular energy status. Elevations of blood glucose during feeding stimulate insulin release from pancreatic

Poids moléculaire: 80 kDa

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis