CST3 anticorps

N° du produit ABIN969070

Cet anticorps Souris Monoclonal détecte spécifiquement CST3 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CST3 anticorps (ABIN969070)

Antigène: CST3 (Cystatin C (CST3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CST3 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5H2

Détail du produit anti-CST3 anticorps

Fonction: CST3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CST3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CST3 (ABIN969070)

Helisalmi, Väkevä, Hiltunen, Soininen: "Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease." dans: Dementia and geriatric cognitive disorders, Vol. 27, Issue 4, pp. 318-21, (2009) (PubMed).

Rehman, Fought, Solomon: "N-acetylcysteine effect on serum creatinine and cystatin C levels in CKD patients." dans: Clinical journal of the American Society of Nephrology : CJASN, Vol. 3, Issue 6, pp. 1610-4, (2008) (PubMed).

Détails sur CST3

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: CST3

Sujet: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. (provided by RefSeq)Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

Poids moléculaire: 42 kDa

ID gène: 1471

UniProt: P01034