ETV1 anticorps (AA 1-191)

N° du produit ABIN969120

Cet anticorps anti-ETV1 est un anticorps Souris Monoclonal détectant ETV1 dans ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ETV1 anticorps (AA 1-191) (ABIN969120)

Antigène: ETV1 (Ets Variant 1 (ETV1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ETV1 est non-conjugé

Application: ELISA

Clone: 1C8B6

Détail du produit anti-ETV1 anticorps

Épitope: AA 1-191

Fonction: ETV1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ETV1 (ABIN969120)

Cerveira, Ribeiro, Peixoto, Costa, Henrique, Jerónimo, Teixeira: "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions." dans: Neoplasia (New York, N.Y.), Vol. 8, Issue 10, pp. 826-32, (2006) (PubMed).

Détails sur ETV1

Antigène: ETV1 (Ets Variant 1 (ETV1))

Autre désignation: ETV1

Sujet: ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

ID gène: 2115

UniProt: P50549