FABP2 anticorps

N° du produit ABIN969124

Cet anticorps Souris Monoclonal détecte spécifiquement FABP2 dans WB, IHC, ELISA, ICC et FACS. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour FABP2 anticorps (ABIN969124)

Antigène: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 9A9B7B3

Détail du produit anti-FABP2 anticorps

Fonction: FABP2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human FABP2 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FABP2 (ABIN969124)

Fisher, Li, Burwinkel, Kühr, Hoffmann, Möhlig, Spranger, Pfeiffer, Boeing, Schrezenmeir, Döring: "Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort." dans: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 38, Issue 5, pp. 341-5, (2006) (PubMed).

Kim, Yun, Byun, Yoo, Lee, Suh: "Codon 54 polymorphism of the fatty acid binding protein 2 gene is associated with increased fat oxidation and hyperinsulinemia, but not with intestinal fatty acid absorption in Korean men." dans: Metabolism: clinical and experimental, Vol. 50, Issue 4, pp. 473-6, (2001) (PubMed).

Georgopoulos, Aras, Tsai: "Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes." dans: The Journal of clinical endocrinology and metabolism, Vol. 85, Issue 9, pp. 3155-60, (2000) (PubMed).

Détails sur FABP2

Antigène: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Autre désignation: FABP2

Sujet:

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.

Poids moléculaire: 15 kDa

ID gène: 2169

UniProt: P12104