GATA3 anticorps

N° du produit ABIN969168

Cet anticorps anti-GATA3 est un anticorps Souris Monoclonal détectant GATA3 dans ELISA et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour GATA3 anticorps (ABIN969168)

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GATA3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 7B5

Détail du produit anti-GATA3 anticorps

Fonction: GATA3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human GATA3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-GATA3 (ABIN969168)

Muzzioli, Stecconi, Moresi, Provinciali: "Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages." dans: Biogerontology, Vol. 10, Issue 5, pp. 593-604, (2009) (PubMed).

van Hamburg, Mus, de Bruijn, de Vogel, Boon, Cornelissen, Asmawidjaja, Hendriks, Lubberts: "GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis." dans: Arthritis and rheumatism, Vol. 60, Issue 3, pp. 750-9, (2009) (PubMed).

Détails sur GATA3

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Autre désignation: GATA3

Sujet: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.

Poids moléculaire: 48 kDa

ID gène: 2625

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation