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GPI anticorps

GPI Reactivité: Humain WB, ELISA, IHC, ICC Hôte: Souris Monoclonal 1B7D7 unconjugated
N° du produit ABIN969176
  • Antigène Voir toutes GPI Anticorps
    GPI (Glucose-6-Phosphate Isomerase (GPI))
    Reactivité
    • 72
    • 53
    • 12
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 102
    • 13
    • 1
    Souris
    Clonalité
    • 97
    • 19
    Monoclonal
    Conjugué
    • 59
    • 9
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GPI est non-conjugé
    Application
    • 92
    • 48
    • 21
    • 16
    • 15
    • 14
    • 14
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human GPI expressed in E. coli.
    Clone
    1B7D7
    Isotype
    IgG1
    Top Product
    Discover our top product GPI Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Schaller, Stohl, Benoit, Tan, Johansen, Ditzel: "Patients with inflammatory arthritic diseases harbor elevated serum and synovial fluid levels of free and immune-complexed glucose-6-phosphate isomerase (G6PI)." dans: Biochemical and biophysical research communications, Vol. 349, Issue 2, pp. 838-45, (2006) (PubMed).

    Haga, Komazaki, Funasaka, Hashimoto, Yokoyama, Watanabe, Raz, Nagase: "AMF/G6PI induces differentiation of leukemic cells via an unknown receptor that differs from gp78." dans: Leukemia & lymphoma, Vol. 47, Issue 10, pp. 2234-43, (2006) (PubMed).

    Muraki, Matsumoto, Chino, Hayashi, Suzuki, Goto, Ito, Murata, Tsutsumi, Sumida: "Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production." dans: Biochemical and biophysical research communications, Vol. 323, Issue 2, pp. 518-22, (2004) (PubMed).

  • Antigène
    GPI (Glucose-6-Phosphate Isomerase (GPI))
    Autre désignation
    Glucose-6-phosphate isomerase (GPI Produits)
    Synonymes
    anticorps PGI, anticorps Amf, anticorps Gpi1, anticorps GPI, anticorps DDBDRAFT_0185620, anticorps DDBDRAFT_0231026, anticorps DDB_0185620, anticorps DDB_0231026, anticorps CG8251, anticorps Dmel\\CG8251, anticorps Gpi, anticorps pgi, anticorps Gpi-1, anticorps Gpi-1r, anticorps Gpi-1s, anticorps Gpi-1t, anticorps Gpi1-r, anticorps Gpi1-s, anticorps Gpi1-t, anticorps Gpi1s, anticorps MF, anticorps NK, anticorps NK/GPI, anticorps Org, anticorps AMF, anticorps GNPI, anticorps NLK, anticorps PHI, anticorps SA-36, anticorps SA36, anticorps gpi, anticorps pgi-2, anticorps glucose-6-phosphate isomerase, anticorps gpi, anticorps glucose-6-phosphate isomerase 1, anticorps gpi Glucose-6-phosphate isomerase, anticorps Phosphoglucose isomerase, anticorps glucose phosphate isomerase 1, anticorps glucose-6-phosphate isomerase b, anticorps GPI, anticorps Gpi, anticorps gpi, anticorps pgi, anticorps GPI1, anticorps Pgi, anticorps Gpi1, anticorps gpib
    Classe de substances
    Viral Protein
    Sujet

    Description: Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

    Aliases: AMF, NLK, PGI, PHI, GNPI, SA-36, GPI

    Poids moléculaire
    63 kDa
    ID gène
    2821
    HGNC
    2821
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