Glutamate Receptor 3 anticorps

N° du produit ABIN969177

Cité dans 2 publications. Cet anticorps anti-Glutamate Receptor 3 Monoclonal Souris (Clone 1D2) (ABIN969177) détecte spécifiquement Glutamate Receptor 3 dans ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Glutamate Receptor 3 anticorps (ABIN969177)

Antigène: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glutamate Receptor 3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 1D2

Détail du produit anti-Glutamate Receptor 3 anticorps

Fonction: GRIA3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human GRIA3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Glutamate Receptor 3 (ABIN969177)

Utge, Soronen, Partonen, Loukola, Kronholm, Pirkola, Nyman, Porkka-Heiskanen, Paunio: "A population-based association study of candidate genes for depression and sleep disturbance." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 2, pp. 468-76, (2010) (PubMed).

Bonnet, Leheup, Béri, Philippe, Grégoire, Jonveaux: "Aberrant GRIA3 transcripts with multi-exon duplications in a family with X-linked mental retardation." dans: American journal of medical genetics. Part A, Vol. 149A, Issue 6, pp. 1280-9, (2009) (PubMed).

Détails sur Glutamate Receptor 3

Antigène: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Autre désignation: GRIA3

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Poids moléculaire: 101 kDa

ID gène: 2892

UniProt: P42263

Pathways: Signalisation PI3K-Akt, cAMP Metabolic Process, Synaptic Membrane