HPRT1 anticorps

N° du produit ABIN969197

L’anticorps Souris Monoclonal anti-HPRT1 a été validé pour ELISA. Il convient pour détecter HPRT1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour HPRT1 anticorps (ABIN969197)

Antigène: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HPRT1 est non-conjugé

Application: ELISA

Clone: 1F8D11

Détail du produit anti-HPRT1 anticorps

Fonction: HPRT Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of HPRT expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-HPRT1 (ABIN969197)

Manjanatha, Shelton, Bishop, Shaddock, Dobrovolsky, Heflich, Webb, Blankenship, Beland, Greenlees, Culp: "Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green." dans: Mutation research, Vol. 547, Issue 1-2, pp. 5-18, (2004) (PubMed).

Détails sur HPRT1

Antigène: HPRT1 (Hypoxanthine phosphoribosyltransferase 1 (HPRT1))

Autre désignation: HPRT

Sujet: The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy . This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.

UniProt: P00492

Pathways: Ribonucleoside Biosynthetic Process