HSPD1 anticorps

N° du produit ABIN969200

Il existe 2+ publications pour ce produit. L’anticorps anti-HSPD1 Monoclonal Souris est utilisé pour la détection de HSPD1 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, IHC, FACS, ELISA et ICC.

Aperçu rapide pour HSPD1 anticorps (ABIN969200)

Antigène: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSPD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Clone: 3G8

Détail du produit anti-HSPD1 anticorps

Fonction: HSP60 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human HSP60 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-HSPD1 (ABIN969200)

López-Hoyos, Alvarez, Ruiz Soto, Blanco, José Bartolomé, Martínez-Taboada: "Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients." dans: Clinical and experimental rheumatology, Vol. 26, Issue 6, pp. 1107-10, (2009) (PubMed).

Glaessgen, Jonmarker, Lindberg, Nilsson, Lewensohn, Ekman, Valdman, Egevad: "Heat shock proteins 27, 60 and 70 as prognostic markers of prostate cancer." dans: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 116, Issue 10, pp. 888-95, (2009) (PubMed).

Détails sur HSPD1

Antigène: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Autre désignation: HSP60

Sujet: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. (provided by RefSeq)

Poids moléculaire: 61 kDa

ID gène: 3329

UniProt: P10809

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity