ICAM1 anticorps (AA 28-480)

N° du produit ABIN969206

Il existe 1 publication pour ce produit. L’anticorps anti-ICAM1 Monoclonal Souris est utilisé pour la détection de ICAM1 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour ICAM1 anticorps (AA 28-480) (ABIN969206)

Antigène: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ICAM1 est non-conjugé

Application: ELISA

Clone: 6G12

Détail du produit anti-ICAM1 anticorps

Épitope: AA 28-480

Fonction: ICAM1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ICAM1 (ABIN969206)

Yang, Cullen, Li, Chapman, Jewell: "Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1." dans: Journal of hepatology, Vol. 40, Issue 3, pp. 375-9, (2004) (PubMed).

Détails sur ICAM1

Antigène: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Autre désignation: ICAM1

Sujet: ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

Poids moléculaire: 57.8 kDa

ID gène: 3383

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling