IGF2BP3 anticorps

N° du produit ABIN969208

Cet anticorps Souris Monoclonal détecte spécifiquement IGF2BP3 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour IGF2BP3 anticorps (ABIN969208)

Antigène: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF2BP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 8F11

Détail du produit anti-IGF2BP3 anticorps

Fonction: IGF2BP3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human IGF2BP3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IGF2BP3 (ABIN969208)

Sitnikova, Mendese, Liu, Woda, Lu, Dresser, Mohanty, Rock, Jiang: "IMP3 predicts aggressive superficial urothelial carcinoma of the bladder." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 6, pp. 1701-6, (2008) (PubMed).

Détails sur IGF2BP3

Antigène: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Autre désignation: IGF2BP3

Sujet: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.Tissue specificity: Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines .IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

Poids moléculaire: 69 kDa

UniProt: O00425