Ki-67 anticorps

N° du produit ABIN969234

Cité dans 2 publications. Cet anticorps anti-Ki-67 Monoclonal Souris (Clone 8D5) (ABIN969234) détecte spécifiquement Ki-67 dans IHC, WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Ki-67 anticorps (ABIN969234)

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ki-67 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Clone: 8D5

Détail du produit anti-Ki-67 anticorps

Fonction: KI67 Antibody

Séquence: CEDLAGFKEL FQTPG

Purification: Ascitic fluid

Immunogène: Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Ki-67 (ABIN969234)

Uzüm, Ataoğlu: "Histopathological parameters with Ki-67 and bcl-2 in the prognosis of meningiomas according to WHO 2000 classification." dans: Tumori, Vol. 94, Issue 3, pp. 389-97, (2008) (PubMed).

Kasprzak, Adamek, Biczysko, Seidel, Przybyszewska, Olejniczak, Juszczyk, Zabel: "Intracellular expression of the proliferative marker Ki-67 and viral proteins (NS3, NS5A and C) in chronic, long lasting hepatitis C virus (HCV) infection." dans: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 45, Issue 4, pp. 357-66, (2007) (PubMed).

Détails sur Ki-67

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Autre désignation: KI67

Sujet: Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Poids moléculaire: 358 kDa

ID gène: 4288

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process