KLHL1 anticorps

N° du produit ABIN969241

Cet anticorps Souris Monoclonal détecte spécifiquement KLHL1 dans ELISA et ICC. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour KLHL1 anticorps (ABIN969241)

Antigène: KLHL1 (Kelch-Like 1 (KLHL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KLHL1 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Clone: 3A8

Détail du produit anti-KLHL1 anticorps

Fonction: KLHL1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human KLHL1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-KLHL1 (ABIN969241)

Barrios-Rodiles, Brown, Ozdamar, Bose, Liu, Donovan, Shinjo, Liu, Dembowy, Taylor, Luga, Przulj, Robinson, Suzuki, Hayashizaki, Jurisica, Wrana: "High-throughput mapping of a dynamic signaling network in mammalian cells." dans: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, (2005) (PubMed).

Détails sur KLHL1

Antigène: KLHL1 (Kelch-Like 1 (KLHL1))

Autre désignation: KLHL1

Sujet: The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.

Poids moléculaire: 82 kDa

ID gène: 57626

UniProt: Q9NR64