KRT15 anticorps

N° du produit ABIN969250

Cet anticorps Souris Monoclonal détecte spécifiquement KRT15 dans IHC, FACS, ELISA et ICC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour KRT15 anticorps (ABIN969250)

Antigène: KRT15 (Keratin 15 (KRT15))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KRT15 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Clone: 6E7

Détail du produit anti-KRT15 anticorps

Fonction: KRT15 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of KRT15 expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-KRT15 (ABIN969250)

Radoja, Stojadinovic, Waseem, Tomic-Canic, Milisavljevic, Teebor, Blumenberg: "Thyroid hormones and gamma interferon specifically increase K15 keratin gene transcription." dans: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3168-79, (2004) (PubMed).

Werner, Munz: "Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo." dans: Experimental cell research, Vol. 254, Issue 1, pp. 80-90, (2000) (PubMed).

Détails sur KRT15

Antigène: KRT15 (Keratin 15 (KRT15))

Autre désignation: KRT15

Sujet: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

Poids moléculaire: 49 kDa

ID gène: 3866

UniProt: P19012