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KRT15 anticorps

KRT15 Reactivité: Humain WB, IHC, FACS, ELISA, ICC Hôte: Souris Monoclonal 6-00E-07 unconjugated
N° du produit ABIN969250
  • Antigène Voir toutes KRT15 Anticorps
    KRT15 (Keratin 15 (KRT15))
    Reactivité
    • 89
    • 32
    • 28
    • 15
    • 2
    Humain
    Hôte
    • 62
    • 30
    • 2
    Souris
    Clonalité
    • 54
    • 40
    Monoclonal
    Conjugué
    • 47
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KRT15 est non-conjugé
    Application
    • 54
    • 28
    • 22
    • 21
    • 17
    • 16
    • 15
    • 14
    • 14
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of KRT15 expressed in E. coli.
    Clone
    6-00E-07
    Isotype
    IgG2a
    Top Product
    Discover our top product KRT15 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Radoja, Stojadinovic, Waseem, Tomic-Canic, Milisavljevic, Teebor, Blumenberg: "Thyroid hormones and gamma interferon specifically increase K15 keratin gene transcription." dans: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3168-79, (2004) (PubMed).

    Werner, Munz: "Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo." dans: Experimental cell research, Vol. 254, Issue 1, pp. 80-90, (2000) (PubMed).

  • Antigène
    KRT15 (Keratin 15 (KRT15))
    Autre désignation
    KRT15 (KRT15 Produits)
    Synonymes
    anticorps xlk2, anticorps CK15, anticorps K15, anticorps K1CO, anticorps AI528832, anticorps Krt1-15, anticorps Ka15, anticorps wu:fa91c06, anticorps wu:fa95d04, anticorps zgc:55334, anticorps keratin 15, type I L homeolog, anticorps keratin 15, type I, anticorps keratin 15, anticorps krt15.L, anticorps krt15, anticorps KRT15, anticorps Krt15
    Sujet

    Description: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

    Aliases: K15, CK15, K1CO, KRT1

    Poids moléculaire
    49 kDa
    ID gène
    3866
    HGNC
    3866
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