MMP1 anticorps

N° du produit ABIN969287

Il existe 2+ publications pour ce produit. L’anticorps anti-MMP1 Monoclonal Souris est utilisé pour la détection de MMP1 dans des échantillons de Humain. Il a été validé pour IHC, ELISA, ICC et FACS.

Aperçu rapide pour MMP1 anticorps (ABIN969287)

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 6A5

Détail du produit anti-MMP1 anticorps

Fonction: MMP1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MMP1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MMP1 (ABIN969287)

Genevay, Finckh, Mezin, Tessitore, Guerne: "Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation." dans: Arthritis research & therapy, Vol. 11, Issue 6, pp. R169, (2010) (PubMed).

Guan, Shu, Fu, Liu, Xu, Wu: "Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells." dans: FEMS microbiology letters, Vol. 299, Issue 2, pp. 214-22, (2009) (PubMed).

Détails sur MMP1

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Autre désignation: MMP1

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 54 kDa

ID gène: 4312

UniProt: P08253