MSI2 anticorps

N° du produit ABIN969295

Cet anticorps Souris Monoclonal détecte spécifiquement MSI2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour MSI2 anticorps (ABIN969295)

Antigène: MSI2 (Musashi Homolog 2 (MSI2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MSI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2C11

Détail du produit anti-MSI2 anticorps

Fonction: MSI2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MSI2 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MSI2 (ABIN969295)

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

De Weer, Speleman, Cauwelier, Van Roy, Yigit, Verhasselt, De Moerloose, Benoit, Noens, Selleslag, Lippert, Struski, Bastard, De Paepe, Vandenberghe, Hagemeijer, Dastugue, Poppe: "EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22." dans: Haematologica, Vol. 93, Issue 12, pp. 1903-7, (2008) (PubMed).

Détails sur MSI2

Antigène: MSI2 (Musashi Homolog 2 (MSI2))

Autre désignation: MSI2

Sujet: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous, detected at low levels.

Poids moléculaire: 35 kDa

UniProt: Q96DH6