MTHFR anticorps

N° du produit ABIN969297

Cité dans 2 publications. Cet anticorps anti-MTHFR Monoclonal Souris (Clone 5D3) (ABIN969297) détecte spécifiquement MTHFR dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour MTHFR anticorps (ABIN969297)

Antigène: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MTHFR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 5D3

Détail du produit anti-MTHFR anticorps

Fonction: MTHFR Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MTHFR expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MTHFR (ABIN969297)

Sarecka-Hujar, Zak, Krauze: "Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease." dans: Kardiologia polska, Vol. 66, Issue 12, pp. 1269-77, (2009) (PubMed).

Oliveira, Bianco, Bianco, Verreschi, Guedes, Galera, Galera, Barbosa, Lipay: "Prevalence of the polymorphism MTHFR A1298C and not MTHFR C677T is related to chromosomal aneuploidy in Brazilian Turner Syndrome patients." dans: Arquivos brasileiros de endocrinologia e metabologia, Vol. 52, Issue 8, pp. 1374-81, (2009) (PubMed).

Détails sur MTHFR

Antigène: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Autre désignation: MTHFR

Sujet: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Poids moléculaire: 75 kDa

ID gène: 4524

UniProt: P42898

Pathways: Methionine Biosynthetic Process