MTHFR anticorps

N° du produit ABIN969297

Détail du produit anti-MTHFR anticorps

Antigène: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MTHFR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human MTHFR expressed in E. coli.

Clone: 5D3

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-MTHFR (ABIN969297)

Sarecka-Hujar, Zak, Krauze: "Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease." dans: Kardiologia polska, Vol. 66, Issue 12, pp. 1269-77, (2009) (PubMed).

Oliveira, Bianco, Bianco, Verreschi, Guedes, Galera, Galera, Barbosa, Lipay: "Prevalence of the polymorphism MTHFR A1298C and not MTHFR C677T is related to chromosomal aneuploidy in Brazilian Turner Syndrome patients." dans: Arquivos brasileiros de endocrinologia e metabologia, Vol. 52, Issue 8, pp. 1374-81, (2009) (PubMed).

Détails sur MTHFR

Antigène: MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Autre désignation: MTHFR (MTHFR Produits)

Synonymes: anticorps DDBDRAFT_0204686, anticorps DDBDRAFT_0230137, anticorps DDB_0204686, anticorps DDB_0230137, anticorps AI323986, anticorps methylenetetrahydrofolate reductase (NAD(P)H) L homeolog, anticorps methylenetetrahydrofolate reductase, anticorps methylenetetrahydrofolate reductase (NAD(P)H), anticorps 5,10-methylenetetrahydrofolate reductase, anticorps mthfr.L, anticorps MTHFR, anticorps mthfr, anticorps metF, anticorps DDB_G0279137, anticorps Mthfr

Sujet:

Description: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Aliases: MTHFR

Poids moléculaire: 75 kDa

ID gène: 4524

HGNC: 4524

Pathways: Methionine Biosynthetic Process