NCOA3 anticorps (AA 1-200)

N° du produit ABIN969309

Cet anticorps anti-NCOA3 est un anticorps Souris Monoclonal détectant NCOA3 dans ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour NCOA3 anticorps (AA 1-200) (ABIN969309)

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCOA3 est non-conjugé

Application: ELISA

Clone: 2C11B12

Détail du produit anti-NCOA3 anticorps

Épitope: AA 1-200

Fonction: NCOA3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NCOA3 (ABIN969309)

Rangel, Torabian, Shaikh, Nosrati, Baehner, Haqq, Leong, Miller, Sagebiel, Kashani-Sabet: "Prognostic significance of nuclear receptor coactivator-3 overexpression in primary cutaneous melanoma." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 24, Issue 28, pp. 4565-9, (2006) (PubMed).

Zheng, Wu, Smith, OMalley: "Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor." dans: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8273-84, (2005) (PubMed).

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: NCOA3

Sujet: NCOA3: nuclear receptor coactivator 3. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

UniProt: Q9Y6Q9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha