NKX3-1 anticorps

N° du produit ABIN969316

Cet anticorps Souris Monoclonal détecte spécifiquement NKX3-1 dans WB, IHC, ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour NKX3-1 anticorps (ABIN969316)

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 4H4

Détail du produit anti-NKX3-1 anticorps

Fonction: NKX3A Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human NKX3A expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NKX3-1 (ABIN969316)

Zhang, Liu, Zhang, Guan, Chen, Cui, Liu, Jiang: "Gene expression profiles in the PC-3 human prostate cancer cells induced by NKX3.1." dans: Molecular biology reports, Vol. 37, Issue 3, pp. 1505-12, (2010) (PubMed).

Lee, Jadhav, Ayer, Rojas, Hyong, Lekic, Stier, Martin, Zhang: "The antioxidant effects of melatonin in surgical brain injury in rats." dans: Acta neurochirurgica. Supplement, Vol. 102, pp. 367-71, (2009) (PubMed).

Zhang, Fillmore, Zimmer: "Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 233, Issue 3, pp. 297-309, (2008) (PubMed).

Jiang, Yu, Zhang, Chen, Liu, Hu, Zhang: "p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line." dans: Experimental & molecular medicine, Vol. 38, Issue 6, pp. 625-33, (2007) (PubMed).

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3A

Sujet: Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.

Poids moléculaire: 26.3 kDa

ID gène: 4824

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus