p63alpha anticorps
Aperçu rapide pour p63alpha anticorps (ABIN969337)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- p63a Antibody
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Purification
- Ascitic fluid
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Immunogène
- Synthesized peptide of human p63alpha.
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Isotype
- IgG1
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth." dans: Cancer research, Vol. 68, Issue 13, pp. 5122-31, (2008) (PubMed).
: "R298Q mutation of p63 gene in autosomal dominant ectodermal dysplasia associated with arrhythmogenic right ventricular cardiomyopathy." dans: European journal of medical genetics, Vol. 51, Issue 5, pp. 497-500, (2008) (PubMed).
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- p63alpha
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Autre désignation
- p63a
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Sujet
- The p63 gene is a homologue of the p53 tumor suppressor gene. Like p53, p63 contains a transactivation (TA) domain induce the transcription of target genes, a DNA binding domain, and an oligomerization domain (OD), used to form tetramers. In contrast to p53, the p63 gene encodes for at least six major isotypes. Three isotypes (TAp63a, TAp63
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Poids moléculaire
- 51 kDa
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ID gène
- 8626
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UniProt
- Q9H3D4
Antigène
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