PGA5 anticorps

N° du produit ABIN969350

L’anticorps Souris Monoclonal anti-PGA5 a été validé pour WB, ELISA et IHC. Il convient pour détecter PGA5 dans des échantillons de Humain.

Aperçu rapide pour PGA5 anticorps (ABIN969350)

Antigène: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PGA5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2C1

Détail du produit anti-PGA5 anticorps

Fonction: PGA5 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human PGA5 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PGA5

Antigène: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Autre désignation: PGA5

Sujet: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

Poids moléculaire: 42 kDa

ID gène: 5222

UniProt: P0DJD9