PGA5 anticorps

N° du produit ABIN969350

Détail du produit anti-PGA5 anticorps

Antigène: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PGA5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human PGA5 expressed in E. coli.

Clone: 2C1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur PGA5

Antigène: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Autre désignation: PGA5 (PGA5 Produits)

Synonymes: anticorps PGA3, anticorps PGA4, anticorps 1110035E17Rik, anticorps Pepf, anticorps pepsinogen 5, group I (pepsinogen A), anticorps pepsinogen 5, group I, anticorps PGA5, anticorps Pga5

Sujet:

Description: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

Aliases: Pepsinogen 5, Pepsin A

Poids moléculaire: 42 kDa

ID gène: 5222

HGNC: 5222