RBP4 anticorps
Aperçu rapide pour RBP4 anticorps (ABIN969380)
Antigène
Voir toutes RBP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- RBP4 Antibody
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of human RBP expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "An RBP4 promoter polymorphism increases risk of type 2 diabetes." dans: Diabetologia, Vol. 51, Issue 8, pp. 1423-8, (2008) (PubMed).
: "High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus." dans: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 8, pp. 3142-8, (2008) (PubMed).
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: "An RBP4 promoter polymorphism increases risk of type 2 diabetes." dans: Diabetologia, Vol. 51, Issue 8, pp. 1423-8, (2008) (PubMed).
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- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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Autre désignation
- RBP4
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Sujet
- This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. (provided by RefSeq)
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Poids moléculaire
- 23 kDa
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UniProt
- P02753
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Pathways
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
Antigène
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