Reticulon 3 anticorps

N° du produit ABIN969387

Cet anticorps anti-Reticulon 3 est un anticorps Souris Monoclonal détectant Reticulon 3 dans ELISA et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 4+ publications.

Aperçu rapide pour Reticulon 3 anticorps (ABIN969387)

Antigène: Reticulon 3 (RTN3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reticulon 3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 10A8

Détail du produit anti-Reticulon 3 anticorps

Fonction: RTN3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of RTN3 expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Reticulon 3 (ABIN969387)

Kim, Chai, Ryu: "Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion." dans: Biochemical and biophysical research communications, Vol. 330, Issue 4, pp. 1095-102, (2005) (PubMed).

Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." dans: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).

Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." dans: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).

Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).

Détails sur Reticulon 3

Antigène: Reticulon 3 (RTN3)

Autre désignation: RTN3

Sujet: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

Poids moléculaire: 113 kDa

UniProt: O95197