RUNX1 anticorps

N° du produit ABIN969390

Cet anticorps anti-RUNX1 est un anticorps Souris Monoclonal détectant RUNX1 dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour RUNX1 anticorps (ABIN969390)

Antigène: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RUNX1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2B5

Détail du produit anti-RUNX1 anticorps

Fonction: RUNX1 Antibody

Purification: Ascitic fluid

Immunogène: Synthesized peptide of human RUNX1.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-RUNX1 (ABIN969390)

Marshall, Moore, Ohki, Kitabayashi, Patterson, Ornelles: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." dans: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).

Ichikawa, Goyama, Asai, Kawazu, Nakagawa, Takeshita, Chiba, Ogawa, Kurokawa: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, (2008) (PubMed).

Détails sur RUNX1

Antigène: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Autre désignation: RUNX1

Sujet: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Poids moléculaire: 55 kDa

ID gène: 861

UniProt: Q01196