SND1 anticorps (AA 361-485)

N° du produit ABIN969411

Cet anticorps anti-SND1 est un anticorps Souris Monoclonal détectant SND1 dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour SND1 anticorps (AA 361-485) (ABIN969411)

Antigène: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SND1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2D7

Détail du produit anti-SND1 anticorps

Épitope: AA 361-485

Fonction: SND1/P100 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SND1 (ABIN969411)

Broadhurst, Lee, Hawkins, Wheeler: "The p100 EBNA-2 coactivator: a highly conserved protein found in a range of exocrine and endocrine cells and tissues in cattle." dans: Biochimica et biophysica acta, Vol. 1681, Issue 2-3, pp. 126-33, (2005) (PubMed).

Tijms, Snijder: "Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100." dans: The Journal of general virology, Vol. 84, Issue Pt 9, pp. 2317-22, (2003) (PubMed).

Détails sur SND1

Antigène: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Autre désignation: SND1/P100

Sujet: SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

Poids moléculaire: 102 kDa

UniProt: Q7KZF4