SUZ12 anticorps

N° du produit ABIN969427

Cet anticorps Souris Monoclonal détecte spécifiquement SUZ12 dans ELISA et ICC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour SUZ12 anticorps (ABIN969427)

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SUZ12 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Clone: 2C11

Détail du produit anti-SUZ12 anticorps

Fonction: SUZ12 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human SUZ12 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SUZ12 (ABIN969427)

Pasini, Hansen, Christensen, Agger, Cloos, Helin: "Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2." dans: Genes & development, Vol. 22, Issue 10, pp. 1345-55, (2008) (PubMed).

Li, Ma, Wang, Koontz, Nucci, Sklar: "Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 50, pp. 20001-6, (2007) (PubMed).

Détails sur SUZ12

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Autre désignation: SUZ12

Sujet: This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. (Provided by RefSeq) SUZ12 is overexpressed in several human tumors, including tumors of the colon, breast and liver.Tissue specificity: Overexpressed in breast and colon cancer.

Poids moléculaire: 83.1 kDa

ID gène: 23512

UniProt: Q15022