Tec Protein Tyrosine Kinase (TEC) anticorps

N° du produit ABIN969434

Il existe 4+ publications pour ce produit. L’anticorps anti-Tec Protein Tyrosine Kinase Monoclonal Souris est utilisé pour la détection de Tec Protein Tyrosine Kinase dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) anticorps (ABIN969434)

Antigène: Tec Protein Tyrosine Kinase (TEC)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA

Clone: 3A5

Détail du produit

Fonction: TEC Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of TEC expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Référence

Jolkver, Emer, Ballan, Krämer, Eikmanns, Marin: "Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum." dans: Journal of bacteriology, Vol. 191, Issue 3, pp. 940-8, (2009) (PubMed).

van Dijk, van Den Akker, Amelsvoort, Mano, Löwenberg, von Lindern: "Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells." dans: Blood, Vol. 96, Issue 10, pp. 3406-13, (2000) (PubMed).

Tsai, Chow, Chen, Huang, Hong, Jan, Kuo, Tsao, Chen, Cheng: "Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing." dans: The Journal of biological chemistry, Vol. 274, Issue 14, pp. 9455-62, (1999) (PubMed).

Kitanaka, Mano, Conley, Campana: "Expression and activation of the nonreceptor tyrosine kinase Tec in human B cells." dans: Blood, Vol. 91, Issue 3, pp. 940-8, (1998) (PubMed).

Détail du antigène

Antigène: Tec Protein Tyrosine Kinase (TEC)

Autre désignation: TEC

Sujet: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Poids moléculaire: 74 kDa

UniProt: P42680

Pathways: Fc-epsilon Receptor Signaling Pathway