VCAM1 anticorps

N° du produit ABIN969452

Il existe 2+ publications pour ce produit. L’anticorps anti-VCAM1 Monoclonal Souris est utilisé pour la détection de VCAM1 dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour VCAM1 anticorps (ABIN969452)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 6G9

Détail du produit anti-VCAM1 anticorps

Fonction: VCAM1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human VCAM1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-VCAM1 (ABIN969452)

Luo, Fang, Hsieh, Chi, Lin, Hsiao, Wu, Wang, Yang: "Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts." dans: Arthritis and rheumatism, Vol. 62, Issue 1, pp. 105-16, (2010) (PubMed).

Rubio-Guerra, Vargas-Robles, Serrano, Lozano-Nuevo, Escalante-Acosta: "Correlation between the levels of circulating adhesion molecules and atherosclerosis in type-2 diabetic normotensive patients: circulating adhesion molecules and atherosclerosis." dans: Cell adhesion & migration, Vol. 3, Issue 4, pp. 369-72, (2009) (PubMed).

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: VCAM1

Sujet: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.

Poids moléculaire: 81 kDa

ID gène: 7412

UniProt: P19320

Pathways: Carbohydrate Homeostasis