WDR5 anticorps

N° du produit ABIN969456

Cet anticorps anti-WDR5 est un anticorps Souris Monoclonal détectant WDR5 dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour WDR5 anticorps (ABIN969456)

Antigène: WDR5 (WD Repeat Domain 5 (WDR5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WDR5 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 7B11

Détail du produit anti-WDR5 anticorps

Fonction: WDR5 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human WDR5 expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-WDR5 (ABIN969456)

Patel, Vought, Dharmarajan, Cosgrove: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." dans: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur WDR5

Antigène: WDR5 (WD Repeat Domain 5 (WDR5))

Autre désignation: WDR5

Sujet: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

Poids moléculaire: 36.6 kDa

UniProt: P61964