ZBTB16 anticorps

N° du produit ABIN969465

Cet anticorps anti-ZBTB16 est un anticorps Souris Monoclonal détectant ZBTB16 dans WB, ELISA et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ZBTB16 anticorps (ABIN969465)

Antigène: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZBTB16 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 5B3

Détail du produit anti-ZBTB16 anticorps

Fonction: ZBTB16 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ZBTB16 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ZBTB16 (ABIN969465)

Felicetti, Errico, Bottero, Segnalini, Stoppacciaro, Biffoni, Felli, Mattia, Petrini, Colombo, Peschle, Carè: "The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms." dans: Cancer research, Vol. 68, Issue 8, pp. 2745-54, (2008) (PubMed).

Détails sur ZBTB16

Antigène: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Autre désignation: ZBTB16

Sujet: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Poids moléculaire: 74 kDa

UniProt: Q05516

Pathways: Positive Regulation of fat Cell Differentiation