alpha Fetoprotein anticorps

N° du produit ABIN969492

Cet anticorps anti-alpha Fetoprotein est un anticorps Souris Monoclonal détectant alpha Fetoprotein dans WB et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour alpha Fetoprotein anticorps (ABIN969492)

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha Fetoprotein est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 6E6

Détail du produit anti-alpha Fetoprotein anticorps

Fonction: AFP Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human AFP expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-alpha Fetoprotein (ABIN969492)

Noda, Miyoshi, Kitada, Nakahara, Gao, Honke, Shiratori, Moriwaki, Sasaki, Kasahara, Hori, Hayashi, Taniguchi: "The enzymatic basis for the conversion of nonfucosylated to fucosylated alpha-fetoprotein by acyclic retinoid treatment in human hepatoma cells: activation of alpha1-6 fucosyltransferase." dans: Tumour biology, Vol. 23, Issue 4, pp. 202-11, (2002) (PubMed).

Sayar, Yaniv, Goshen, Cohen: "Treatment of alpha-fetoprotein secreting hepatoblastoma by response of serum alpha-fetoprotein levels: a new concept." dans: Pediatric hematology and oncology, Vol. 18, Issue 8, pp. 509-18, (2001) (PubMed).

Détails sur alpha Fetoprotein

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Autre désignation: AFP

Sujet: AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Poids moléculaire: 69 kDa

ID gène: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process