EIF4B anticorps

N° du produit ABIN969517

Cet anticorps Souris Monoclonal détecte spécifiquement EIF4B dans WB, ELISA, IHC, FACS et ICC. Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour EIF4B anticorps (ABIN969517)

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF4B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 1F5

Détail du produit anti-EIF4B anticorps

Fonction: EIF4B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human EIF4B expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EIF4B (ABIN969517)

Mokas, Mills, Garreau, Fournier, Robert, Arya, Kaufman, Pelletier, Mazroui: "Uncoupling stress granule assembly and translation initiation inhibition." dans: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).

Shahbazian, Roux, Mieulet, Cohen, Raught, Taunton, Hershey, Blenis, Pende, Sonenberg: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." dans: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, (2006) (PubMed).

Détails sur EIF4B

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Autre désignation: EIF4B

Sujet: The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F

Poids moléculaire: 80 kDa

ID gène: 1975

UniProt: P23588